Alzheimer’s disease is the cause of progressive dementia, memory loss, and behavior changes. Although there has been no cure found within the past decade, researchers are beginning to focus on a new treatment: transgenic mice with human beta-amyloid plaques in their brains. The article discusses how these transgenic mice can help identify interactions between genetic mutations and brain inflammation.
What are transgenic mice?
Transgenic mice are mice that have had genes from other animals introduced into their cells. Transgenic mice can be used to study diseases in ways that would not be possible with regular mice. They also have the potential to be used in research on treatments for diseases, including Alzheimer’s disease.
The applications of transgenic mouse
Alzheimer’s disease is a fatal neurodegenerative disorder that affects people over the age of 65. There is currently no cure for Alzheimer’s, and the only treatment available is to help manage symptoms. One potential way to treat Alzheimer’s is through the use of transgenic mice. Transgenic mice are mice that have had genes from another species inserted into their DNA. This process allows scientists to study how different genes influence Alzheimer’s Disease. Recently, researchers at the University of California, Davis used transgenic mice to study how a gene called APOE influences Alzheimer’s Disease. The team found that deleting the APOE gene reduced the severity of Alzheimer’s Disease in mouse models. This research could lead to new treatments for Alzheimer’s Disease in humans.
Alzheimer’s disease is a devastating condition that affects millions of people worldwide. There is currently no cure for Alzheimer’s, and current treatments only provide relief from symptoms such as confusion, memory loss, and dementia. One potential way to treat Alzheimer’s is through the use of transgenic mice. If you are interested in transgenic mice, do not hesitate to search Cyagen for more information.